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sleep onset latency (min), 8.9 8.1 vs 7.4 6.8

ELIXA, Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With Lixisenatide

Safety monitoring should include periodic IGF-1 levels and fasting glucose checks, as growth hormone stimulation can affect glucose metabolism

Orforglipron may not surpass the efficacy benchmarks set by injectables like tirzepatide or semaglutide, but its superior convenience over existing oral options might make effective GLP-1 therapy accessible to more patients

Clinical trials have demonstrated that semaglutide produces substantial weight loss when combined with lifestyle modifications including reduced caloric intake and increased physical activity